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TargetDNA damage-inducible transcript 3 protein
LigandBDBM61423
Substrate/Competitorn/a
Meas. Tech.CHOP dose-response primary assay
IC50 7250±n/a nM
Citation PubChem, PC CHOP dose-response primary assay PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
DNA damage-inducible transcript 3 protein
Name:DNA damage-inducible transcript 3 protein
Synonyms:Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153
Type:Enzyme Catalytic Domain
Mol. Mass.:19175.17
Organism:Mus musculus
Description:gi_160707929
Residue:168
Sequence:
MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM61423
n/a
NameBDBM61423
Synonyms:3-tert-Butyl-5-[(4-methyl-benzylamino)-methyl]-1-phenyl-1,7-dihydro-pyrazolo[3,4-b]pyridin-6-one | 3-tert-butyl-5-[[(4-methylbenzyl)amino]methyl]-1-phenyl-2H-pyrazolo[3,4-b]pyridin-6-one | 3-tert-butyl-5-[[(4-methylphenyl)methylamino]methyl]-1-phenyl-2H-pyrazolo[3,4-b]pyridin-6-one | MLS000067257 | SMR000124790 | cid_1383782
TypeSmall organic molecule
Emp. Form.C25H28N4O
Mol. Mass.400.516
SMILESCc1ccc(CNCc2cc3c(nn(-c4ccccc4)c3[nH]c2=O)C(C)(C)C)cc1
Structure
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