Ki Summary

Reaction Details

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Target

Caspase-3

Ligand

BDBM79437

Substrate/Competitor

n/a

Meas. Tech.

Dose response counterscreen for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-3

EC50

>85301±n/a nM

Citation

PubChem, PC Dose response counterscreen for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-3 PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Caspase-3

Name:

Caspase-3

Synonyms:

Type:

Hydrolase; heterotetramer of two heterodimers

Mol. Mass.:

31607.55

Organism:

Homo sapiens (Human)

Description:

n/a

Residue:

277

Sequence:

MENTENSVDSKSIKNLEPKIIHGSESMDSGISLDNSYKMDYPEMGLCIIINNKNFHKSTG
MTSRSGTDVDAANLRETFRNLKYEVRNKNDLTREEIVELMRDVSKEDHSKRSSFVCVLLS
HGEEGIIFGTNGPVDLKKITNFFRGDRCRSLTGKPKLFIIQACRGTELDCGIETDSGVDD
DMACHKIPVEADFLYAYSTAPGYYSWRNSKDGSWFIQSLCAMLKQYADKLEFMHILTRVN
RKVATEFESFSFDATFHAKKQIPCIVSMLTKELYFYH

BDBM79437

n/a

Name

BDBM79437

Synonyms:

2-[(4-ethoxyanilino)methylidene]-5-(2-furanyl)cyclohexane-1,3-dione | 2-[(4-ethoxyanilino)methylidene]-5-(furan-2-yl)cyclohexane-1,3-dione | 2-[[(4-ethoxyphenyl)amino]methylidene]-5-(furan-2-yl)cyclohexane-1,3-dione | 2-{[(4-ethoxyphenyl)amino]methylene}-5-(2-furyl)-1,3-cyclohexanedione | 5-(2-furyl)-2-(p-phenetidinomethylene)cyclohexane-1,3-quinone | MLS000666629 | SMR000268302 | cid_760310

Type

Small organic molecule

Emp. Form.

C19H19NO4

Mol. Mass.

325.3585

SMILES

CCOc1ccc(NC=C2C(=O)CC(CC2=O)c2ccco2)cc1 |(3.08,-8.82,;3.08,-7.28,;4.41,-6.51,;4.41,-4.97,;3.08,-4.2,;3.08,-2.66,;4.41,-1.89,;4.41,-.35,;5.75,.42,;5.75,1.96,;7.08,2.73,;8.41,1.96,;7.08,4.27,;5.75,5.04,;4.41,4.27,;4.41,2.73,;3.08,1.96,;6.52,6.38,;5.89,7.79,;7.04,8.82,;8.37,8.05,;8.05,6.54,;5.75,-2.66,;5.75,-4.2,)|

Structure