| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-7 |
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| Ligand | BDBM79430 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 |
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| EC50 | >85261±n/a nM |
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| Citation |  PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Caspase-7 |
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| Name: | Caspase-7 |
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| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
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| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
|
|
|
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| BDBM79430 |
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| n/a |
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| Name | BDBM79430 |
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| Synonyms: | 3-[2-[4-(dimethylamino)phenyl]-2-keto-ethyl]-6,7-dimethoxy-phthalide | 3-[2-[4-(dimethylamino)phenyl]-2-oxidanylidene-ethyl]-6,7-dimethoxy-3H-2-benzofuran-1-one | 3-[2-[4-(dimethylamino)phenyl]-2-oxoethyl]-6,7-dimethoxy-3H-2-benzofuran-1-one | 3-[2-[4-(dimethylamino)phenyl]-2-oxoethyl]-6,7-dimethoxy-3H-isobenzofuran-1-one | MLS000108118 | SMR000104080 | cid_2864745 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21NO5 |
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| Mol. Mass. | 355.3844 |
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| SMILES | COc1ccc2C(CC(=O)c3ccc(cc3)N(C)C)OC(=O)c2c1OC |
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| Structure | 
|
|---|
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