| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-7 |
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| Ligand | BDBM51685 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 |
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| EC50 | >85260±n/a nM |
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| Citation |  PubChem, PC Dose response assay for dual activators of procaspase-3 and procaspase-7: Absorbance-based biochemical high throughput screening assay to identify activators of procaspase-7 PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Caspase-7 |
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| Name: | Caspase-7 |
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| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
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| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
|
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|
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| BDBM51685 |
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| n/a |
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| Name | BDBM51685 |
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| Synonyms: | 4-methoxy-N-[(8-phenylmethoxy-2-quinolinyl)methylideneamino]benzamide | 4-methoxy-N-[(8-phenylmethoxyquinolin-2-yl)methylideneamino]benzamide | MLS000544514 | N'-{[8-(benzyloxy)-2-quinolinyl]methylene}-4-methoxybenzohydrazide | N-[(8-benzoxy-2-quinolyl)methyleneamino]-4-methoxy-benzamide | SMR000163095 | cid_1237301 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H21N3O3 |
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| Mol. Mass. | 411.4525 |
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| SMILES | COc1ccc(cc1)C(=O)NN=Cc1ccc2cccc(OCc3ccccc3)c2n1 |w:11.11| |
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| Structure | 
|
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