| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin alpha-L |
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| Ligand | BDBM79603 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of Developing T Cell Immune Modulators with powder sourced compounds |
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| EC50 | 299±n/a nM |
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| Citation |  PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Integrin alpha-L |
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| Name: | Integrin alpha-L |
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| Synonyms: | CD11 antigen-like family member A | ITAL_MOUSE | Itgal | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lfa-1 | Ly-15 | Lymphocyte antigen 15 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 128317.79 |
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| Organism: | Mus musculus |
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| Description: | P24063 |
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| Residue: | 1162 |
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| Sequence: | MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKVGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTL
SSPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVS
CEELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENEN
SSLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDH
NMPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPI
VFRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDL
IHEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPL
AVPGEETKDMGCLEPLRESDKD
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| BDBM79603 |
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| n/a |
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| Name | BDBM79603 |
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| Synonyms: | (3-chloranyl-6-fluoranyl-1-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | (3-chloro-6-fluoro-1-benzothiophen-2-yl)-(3,5-dimethyl-1-pyrazolyl)methanone | (3-chloro-6-fluoro-1-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | (3-chloro-6-fluoro-benzothiophen-2-yl)-(3,5-dimethylpyrazol-1-yl)methanone | VU0284248-2 | cid_2948628 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H10ClFN2OS |
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| Mol. Mass. | 308.758 |
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| SMILES | Cc1cc(C)n(n1)C(=O)c1sc2cc(F)ccc2c1Cl |
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| Structure | 
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