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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Integrin alpha-L | ||
| Ligand | BDBM79606 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose Response of Developing T Cell Immune Modulators with powder sourced compounds | ||
| EC50 | 51880±n/a nM | ||
| Citation |  PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Integrin alpha-L | |||
| Name: | Integrin alpha-L | ||
| Synonyms: | CD11 antigen-like family member A | ITAL_MOUSE | Itgal | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lfa-1 | Ly-15 | Lymphocyte antigen 15 | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 128317.79 | ||
| Organism: | Mus musculus | ||
| Description: | P24063 | ||
| Residue: | 1162 | ||
| Sequence: |
| ||
| BDBM79606 | |||
| n/a | |||
| Name | BDBM79606 | ||
| Synonyms: | 4-[[2-[(7-chloranyl-4-oxidanylidene-pyrido[1,2-a]pyrimidin-2-yl)methylsulfanyl]-4-oxidanylidene-thieno[3,2-d]pyrimidin-3-yl]methyl]cyclohexane-1-carboxylic acid | 4-[[2-[(7-chloro-4-keto-pyrido[1,2-a]pyrimidin-2-yl)methylthio]-4-keto-thieno[3,2-d]pyrimidin-3-yl]methyl]cyclohexanecarboxylic acid | 4-[[2-[(7-chloro-4-oxo-2-pyrido[1,2-a]pyrimidinyl)methylthio]-4-oxo-3-thieno[3,2-d]pyrimidinyl]methyl]-1-cyclohexanecarboxylic acid | 4-[[2-[(7-chloro-4-oxopyrido[1,2-a]pyrimidin-2-yl)methylsulfanyl]-4-oxothieno[3,2-d]pyrimidin-3-yl]methyl]cyclohexane-1-carboxylic acid | VU0146817-3 | cid_4170435 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H21ClN4O4S2 | ||
| Mol. Mass. | 517.02 | ||
| SMILES | OC(=O)C1CCC(Cn2c(SCc3cc(=O)n4cc(Cl)ccc4n3)nc3ccsc3c2=O)CC1 |(4.41,-5.21,;4.41,-3.67,;3.08,-2.9,;5.75,-2.9,;7.08,-3.67,;8.41,-2.9,;8.41,-1.36,;9.75,-.59,;9.75,.95,;11.08,1.72,;12.42,.95,;13.75,1.72,;15.08,.95,;15.08,-.59,;16.42,-1.36,;16.42,-2.9,;17.75,-.59,;19.13,-1.41,;20.52,-.62,;21.85,-1.4,;20.52,.98,;19.13,1.77,;17.75,.95,;16.42,1.72,;11.08,3.26,;9.75,4.03,;9.43,5.53,;7.9,5.69,;7.28,4.29,;8.41,3.26,;8.41,1.72,;7.08,.95,;7.08,-.59,;5.75,-1.36,)| | ||
| Structure | 
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