| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin alpha-L |
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| Ligand | BDBM79615 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of Developing T Cell Immune Modulators with powder sourced compounds |
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| EC50 | 29107±n/a nM |
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| Citation |  PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Integrin alpha-L |
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| Name: | Integrin alpha-L |
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| Synonyms: | CD11 antigen-like family member A | ITAL_MOUSE | Itgal | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lfa-1 | Ly-15 | Lymphocyte antigen 15 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 128317.79 |
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| Organism: | Mus musculus |
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| Description: | P24063 |
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| Residue: | 1162 |
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| Sequence: | MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKVGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTL
SSPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVS
CEELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENEN
SSLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDH
NMPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPI
VFRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDL
IHEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPL
AVPGEETKDMGCLEPLRESDKD
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| BDBM79615 |
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| n/a |
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| Name | BDBM79615 |
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| Synonyms: | 1-(2-methylbenzoyl)-N-(4-methyl-3-piperidin-1-ylsulfonylphenyl)piperidine-4-carboxamide | 1-(2-methylphenyl)carbonyl-N-(4-methyl-3-piperidin-1-ylsulfonyl-phenyl)piperidine-4-carboxamide | 1-[(2-methylphenyl)-oxomethyl]-N-[4-methyl-3-(1-piperidinylsulfonyl)phenyl]-4-piperidinecarboxamide | N-(4-methyl-3-piperidinosulfonyl-phenyl)-1-o-toluoyl-isonipecotamide | VU0424160-1 | cid_16277168 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H33N3O4S |
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| Mol. Mass. | 483.623 |
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| SMILES | Cc1ccccc1C(=O)N1CCC(CC1)C(=O)Nc1ccc(C)c(c1)S(=O)(=O)N1CCCCC1 |
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| Structure | 
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