| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin alpha-L |
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| Ligand | BDBM79616 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response of Developing T Cell Immune Modulators with powder sourced compounds |
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| EC50 | 197±n/a nM |
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| Citation |  PubChem, PC Dose Response of Developing T Cell Immune Modulators with powder sourced compounds PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Integrin alpha-L |
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| Name: | Integrin alpha-L |
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| Synonyms: | CD11 antigen-like family member A | ITAL_MOUSE | Itgal | Leukocyte adhesion glycoprotein LFA-1 alpha chain | Leukocyte function-associated molecule 1 alpha chain | Lfa-1 | Ly-15 | Lymphocyte antigen 15 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 128317.79 |
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| Organism: | Mus musculus |
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| Description: | P24063 |
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| Residue: | 1162 |
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| Sequence: | MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKVGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTL
SSPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVS
CEELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENEN
SSLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDH
NMPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPI
VFRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDL
IHEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPL
AVPGEETKDMGCLEPLRESDKD
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| BDBM79616 |
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| n/a |
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| Name | BDBM79616 |
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| Synonyms: | 2-[1,3-benzodioxol-5-ylmethyl(methyl)amino]-N-(2-chloranyl-5-pyrrolidin-1-ylsulfonyl-phenyl)ethanamide | 2-[1,3-benzodioxol-5-ylmethyl(methyl)amino]-N-(2-chloro-5-pyrrolidin-1-ylsulfonylphenyl)acetamide | 2-[1,3-benzodioxol-5-ylmethyl(methyl)amino]-N-[2-chloro-5-(1-pyrrolidinylsulfonyl)phenyl]acetamide | N-(2-chloro-5-pyrrolidinosulfonyl-phenyl)-2-[methyl(piperonyl)amino]acetamide | VU0424162-1 | cid_16329116 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H24ClN3O5S |
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| Mol. Mass. | 465.95 |
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| SMILES | CN(CC(=O)Nc1cc(ccc1Cl)S(=O)(=O)N1CCCC1)Cc1ccc2OCOc2c1 |
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| Structure | 
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