| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Ligand | BDBM77767 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. |
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| IC50 | >100000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM10 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 10303.50 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285809906 |
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| Residue: | 93 |
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| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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| BDBM77767 |
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| n/a |
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| Name | BDBM77767 |
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| Synonyms: | MLS000723710 | N'-[(1E,2Z)-3-(2-furyl)prop-2-enylidene]thiophene-2-carbohydrazide | N-[[(Z)-3-(2-furanyl)prop-2-enylidene]amino]-2-thiophenecarboxamide | N-[[(Z)-3-(2-furyl)prop-2-enylidene]amino]thiophene-2-carboxamide | N-[[(Z)-3-(furan-2-yl)prop-2-enylidene]amino]thiophene-2-carboxamide | SMR000305305 | cid_1584401 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H10N2O2S |
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| Mol. Mass. | 246.285 |
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| SMILES | O=C(NN=C\C=C/c1ccco1)c1cccs1 |
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| Structure | 
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