Reaction Details |
| Report a problem with these data |
Target | Bcl-2-related protein A1 |
---|
Ligand | BDBM78561 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen |
---|
IC50 | 2020±573 nM |
---|
Citation | PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Bcl-2-related protein A1 |
---|
Name: | Bcl-2-related protein A1 |
Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
Type: | Apoptosis regulator protein |
Mol. Mass.: | 19909.74 |
Organism: | Mus musculus (Mouse) |
Description: | gi_11024684 |
Residue: | 172 |
Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
|
|
|
BDBM78561 |
---|
n/a |
---|
Name | BDBM78561 |
Synonyms: | 1-butyl-2-hydroxy-4-keto-N-(2-sulfamoylphenyl)quinoline-3-carboxamide | 1-butyl-2-hydroxy-4-oxo-N-(2-sulfamoylphenyl)-3-quinolinecarboxamide | 1-butyl-2-hydroxy-4-oxo-N-(2-sulfamoylphenyl)quinoline-3-carboxamide | 1-butyl-2-oxidanyl-4-oxidanylidene-N-(2-sulfamoylphenyl)quinoline-3-carboxamide | MLS000061554 | N-[2-(aminosulfonyl)phenyl]-1-butyl-4-hydroxy-2-oxo-1,2-dihydro-3-quinolinecarboxamide | SMR000069884 | cid_1830937 |
Type | Small organic molecule |
Emp. Form. | C20H21N3O5S |
Mol. Mass. | 415.463 |
SMILES | CCCCn1c2ccccc2c(O)c(C(=O)Nc2ccccc2S(N)(=O)=O)c1=O |
Structure |
|