Reaction Details |
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Target | Bcl-2-related protein A1 |
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Ligand | BDBM79184 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen |
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IC50 | 6100±307 nM |
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Citation | PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Bcl-2-related protein A1 |
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Name: | Bcl-2-related protein A1 |
Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
Type: | Apoptosis regulator protein |
Mol. Mass.: | 19909.74 |
Organism: | Mus musculus (Mouse) |
Description: | gi_11024684 |
Residue: | 172 |
Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
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BDBM79184 |
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n/a |
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Name | BDBM79184 |
Synonyms: | KI-RI | MLS002153718 | SMR001231144 | cid_24983198 |
Type | Small organic molecule |
Emp. Form. | C68H120N20O7 |
Mol. Mass. | 1329.8102 |
SMILES | [#6]-[#6]-[#6@H](-[#6])-[#6@@H](-[#6](=O)-[#7]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1nc(-[#7]-[#6]-[#6]-[#8]-[#6]-[#6]-[#8]-[#6]-[#6]-[#8]-[#6]C#C)nc(n1)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-[#6](=O)-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#7]-[#6](=O)-[#6@H](-[#6@@H](-[#6])-[#6]-[#6])-n1cc(-[#6]-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])nn1)-n1cc(-[#6]-[#6]-[#6]-[#6]-[#6]-[#7])nn1 |
Structure |
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