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TargetTropomyosin alpha-1 chain
LigandBDBM32010
Substrate/Competitorn/a
Meas. Tech.Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50 3708±n/a nM
Citation PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tropomyosin alpha-1 chain
Name:Tropomyosin alpha-1 chain
Synonyms:TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:Enzyme Catalytic Domain
Mol. Mass.:32681.01
Organism:Sus scrofa
Description:P42639
Residue:284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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  Blast E-value cutoff:
BDBM32010
n/a
NameBDBM32010
Synonyms:(4Z)-4-[[4-(dimethylamino)anilino]methylene]-2-phenyl-2-oxazolin-5-one | (4Z)-4-[[4-(dimethylamino)anilino]methylidene]-2-phenyl-1,3-oxazol-5-one | (4Z)-4-[[4-(dimethylamino)anilino]methylidene]-2-phenyl-5-oxazolone | (4Z)-4-[[[4-(dimethylamino)phenyl]amino]methylidene]-2-phenyl-1,3-oxazol-5-one | 4-[1-(4-Dimethylamino-phenylamino)-meth-(Z)-ylidene]-2-phenyl-4H-oxazol-5-one | MLS000077184 | SMR000009577 | cid_5378674
TypeSmall organic molecule
Emp. Form.C18H17N3O2
Mol. Mass.307.3465
SMILESCN(C)c1ccc(cc1)N=Cc1nc(oc1O)-c1ccccc1 |w:9.9|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: