| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM79641 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 5397±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM79641 |
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| n/a |
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| Name | BDBM79641 |
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| Synonyms: | (5Z)-3-ethyl-5-(indolin-1-ylmethylene)-2-thioxo-thiazolidin-4-one | (5Z)-5-(2,3-dihydroindol-1-ylmethylidene)-3-ethyl-2-sulfanylidene-1,3-thiazolidin-4-one | (5Z)-5-(2,3-dihydroindol-1-ylmethylidene)-3-ethyl-2-sulfanylidene-4-thiazolidinone | MLS000080529 | SMR000037442 | cid_663616 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14N2OS2 |
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| Mol. Mass. | 290.404 |
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| SMILES | CCN1C(=S)S\C(=C/N2CCc3ccccc23)C1=O |
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| Structure | 
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