| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM41787 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 24431±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM41787 |
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| n/a |
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| Name | BDBM41787 |
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| Synonyms: | 1-amino-4-keto-pyrrol[1,2-a]indole-2-carboxylic acid ethyl ester | 1-amino-4-oxo-2-pyrrolo[1,2-a]indolecarboxylic acid ethyl ester | MLS000058819 | SMR000069085 | cid_611015 | ethyl 1-amino-4-oxopyrrolo[1,2-a]indole-2-carboxylate | ethyl 1-azanyl-4-oxidanylidene-pyrrolo[1,2-a]indole-2-carboxylate | ethyl 3-amino-9-oxo-9H-pyrrolo[1,2-a]indole-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12N2O3 |
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| Mol. Mass. | 256.2567 |
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| SMILES | CCOC(=O)c1cc2C(=O)c3ccccc3-n2c1N |
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| Structure | 
|
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