| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM79661 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 615.36±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
|
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|
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| BDBM79661 |
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| n/a |
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| Name | BDBM79661 |
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| Synonyms: | (Z)-3-(5-Phenyl-furan-2-yl)-2-(4-thiophen-2-yl-thiazol-2-yl)-acrylonitrile | (Z)-3-(5-phenyl-2-furanyl)-2-(4-thiophen-2-yl-2-thiazolyl)-2-propenenitrile | (Z)-3-(5-phenyl-2-furyl)-2-[4-(2-thienyl)thiazol-2-yl]acrylonitrile | (Z)-3-(5-phenylfuran-2-yl)-2-(4-thiophen-2-yl-1,3-thiazol-2-yl)prop-2-enenitrile | MLS000554395 | SMR000146712 | cid_7308510 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H12N2OS2 |
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| Mol. Mass. | 360.452 |
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| SMILES | N#C\C(=C\c1ccc(o1)-c1ccccc1)c1nc(cs1)-c1cccs1 |
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| Structure | 
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