| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
|---|
| Ligand | BDBM43688 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
|---|
| EC50 | 500.48±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tropomyosin alpha-1 chain |
|---|
| Name: | Tropomyosin alpha-1 chain |
|---|
| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 32681.01 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | P42639 |
|---|
| Residue: | 284 |
|---|
| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
|
|
|
|---|
| BDBM43688 |
|---|
| n/a |
|---|
| Name | BDBM43688 |
|---|
| Synonyms: | (E)-2-(1H-Benzoimidazol-2-yl)-3-(5-morpholin-4-yl-furan-2-yl)-acrylonitrile | (E)-2-(1H-benzimidazol-2-yl)-3-(5-morpholin-4-ylfuran-2-yl)prop-2-enenitrile | (E)-2-(1H-benzimidazol-2-yl)-3-(5-morpholino-2-furyl)acrylonitrile | (E)-2-(1H-benzimidazol-2-yl)-3-[5-(4-morpholinyl)-2-furanyl]-2-propenenitrile | MLS000552736 | SMR000146251 | cid_5914490 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H16N4O2 |
|---|
| Mol. Mass. | 320.3452 |
|---|
| SMILES | N#C\C(=C/c1ccc(o1)N1CCOCC1)c1nc2ccccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
