Ki Summary

Reaction Details

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Target

Tropomyosin alpha-1 chain

Ligand

BDBM51079

Substrate/Competitor

n/a

Meas. Tech.

Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)

EC50

1465±n/a nM

Citation

PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Tropomyosin alpha-1 chain

Name:

Tropomyosin alpha-1 chain

Synonyms:

TPM1 | TPM1_PIG | cardiac alpha tropomyosin

Type:

Enzyme Catalytic Domain

Mol. Mass.:

32681.01

Organism:

Sus scrofa

Description:

P42639

Residue:

284

Sequence:

MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI

BDBM51079

n/a

Name

BDBM51079

Synonyms:

MLS000588145 | N-[(5Z)-4-keto-5-[(1-methylindol-3-yl)methylene]-2-thioxo-thiazolidin-3-yl]benzamide | N-[(5Z)-5-[(1-methyl-3-indolyl)methylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]benzamide | N-[(5Z)-5-[(1-methylindol-3-yl)methylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide | N-[(5Z)-5-[(1-methylindol-3-yl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]benzamide | N-{5-[1-(1-Methyl-1H-indol-3-yl)-meth-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-benzamide | SMR000220188 | cid_2009322

Type

Small organic molecule

Emp. Form.

C20H15N3O2S2

Mol. Mass.

393.482

SMILES

Cn1cc(\C=C2/SC(=S)N(NC(=O)c3ccccc3)C2=O)c2ccccc12

Structure