| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
|---|
| Ligand | BDBM79705 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
|---|
| EC50 | >71500±n/a nM |
|---|
| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Tropomyosin alpha-1 chain |
|---|
| Name: | Tropomyosin alpha-1 chain |
|---|
| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 32681.01 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | P42639 |
|---|
| Residue: | 284 |
|---|
| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
|
|
|
|---|
| BDBM79705 |
|---|
| n/a |
|---|
| Name | BDBM79705 |
|---|
| Synonyms: | 2-(4-{[1-(5-chloropyridin-2-yl)-1H-pyrrol-2-yl]methyl}-1-isobutylpiperazin-2-yl)ethanol | 2-[4-[[1-(5-chloranylpyridin-2-yl)pyrrol-2-yl]methyl]-1-(2-methylpropyl)piperazin-2-yl]ethanol | 2-[4-[[1-(5-chloro-2-pyridinyl)-2-pyrrolyl]methyl]-1-(2-methylpropyl)-2-piperazinyl]ethanol | 2-[4-[[1-(5-chloro-2-pyridyl)pyrrol-2-yl]methyl]-1-isobutyl-piperazin-2-yl]ethanol | 2-[4-[[1-(5-chloropyridin-2-yl)pyrrol-2-yl]methyl]-1-(2-methylpropyl)piperazin-2-yl]ethanol | MLS000733260 | SMR000315885 | cid_16187269 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H29ClN4O |
|---|
| Mol. Mass. | 376.923 |
|---|
| SMILES | CC(C)CN1CCN(Cc2cccn2-c2ccc(Cl)cn2)CC1CCO |
|---|
| Structure | 
|
|---|
Search and Browse
