| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM79784 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 1981±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM79784 |
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| n/a |
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| Name | BDBM79784 |
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| Synonyms: | 6-[2-(3-aminophenyl)ethynyl]-2-[4-(dimethylamino)phenyl]-1-benzopyran-4-one | 6-[2-(3-aminophenyl)ethynyl]-2-[4-(dimethylamino)phenyl]chromen-4-one | 6-[2-(3-aminophenyl)ethynyl]-2-[4-(dimethylamino)phenyl]chromone | MLS002473527 | SMR001397695 | cid_44202189 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H20N2O2 |
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| Mol. Mass. | 380.4385 |
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| SMILES | CN(C)c1ccc(cc1)-c1cc(=O)c2cc(ccc2o1)C#Cc1cccc(N)c1 |
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| Structure | 
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