Reaction Details |
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Target | Orexin/Hypocretin receptor type 1 |
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Ligand | BDBM38923 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescence-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) |
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IC50 | 9489±n/a nM |
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Citation | PubChem, PC Fluorescence-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Orexin/Hypocretin receptor type 1 |
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Name: | Orexin/Hypocretin receptor type 1 |
Synonyms: | HCRTR1 | Hypocretin receptor type 1 | OX1R_HUMAN | Orexin receptor type 1 | Orexin receptor type 1 (OR 1) | Orexin receptor type 1 (OR-1) | Orexin receptor type 1 (OX1) | Orexin receptor type 1 (OX1R) | Orexin receptor type 1 (OxR1) | Ox1r |
Type: | Protein |
Mol. Mass.: | 47554.50 |
Organism: | Homo sapiens (Human) |
Description: | O43613 |
Residue: | 425 |
Sequence: | MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
TTVLP
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BDBM38923 |
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n/a |
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Name | BDBM38923 |
Synonyms: | (2-oxidanylideneoxolan-3-yl) 5-(1,3-benzothiazol-2-yl)thiophene-2-carboxylate | (2-oxooxolan-3-yl) 5-(1,3-benzothiazol-2-yl)thiophene-2-carboxylate | 5-(1,3-benzothiazol-2-yl)-2-thiophenecarboxylic acid (2-oxo-3-oxolanyl) ester | 5-(1,3-benzothiazol-2-yl)thiophene-2-carboxylic acid (2-ketotetrahydrofuran-3-yl) ester | MLS000096514 | SMR000062409 | cid_2997660 |
Type | Small organic molecule |
Emp. Form. | C16H11NO4S2 |
Mol. Mass. | 345.393 |
SMILES | O=C(OC1CCOC1=O)c1ccc(s1)-c1nc2ccccc2s1 |
Structure |
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