| Reaction Details |
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 | Report a problem with these data |
| Target | Orexin/Hypocretin receptor type 1 |
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| Ligand | BDBM79825 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) |
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| IC50 | 93.34±n/a nM |
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| Citation |  PubChem, PC Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Orexin/Hypocretin receptor type 1 |
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| Name: | Orexin/Hypocretin receptor type 1 |
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| Synonyms: | HCRTR1 | Hypocretin receptor type 1 | OX1R_HUMAN | Orexin receptor type 1 | Orexin receptor type 1 (OR 1) | Orexin receptor type 1 (OR-1) | Orexin receptor type 1 (OX1) | Orexin receptor type 1 (OX1R) | Orexin receptor type 1 (OxR1) | Ox1r |
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| Type: | Protein |
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| Mol. Mass.: | 47554.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O43613 |
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| Residue: | 425 |
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| Sequence: | MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
TTVLP
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| BDBM79825 |
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| n/a |
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| Name | BDBM79825 |
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| Synonyms: | 1-(5-bromanylthiophen-2-yl)sulfonyl-N-(3-methylsulfanylphenyl)pyrrolidine-2-carboxamide | 1-(5-bromothiophen-2-yl)sulfonyl-N-(3-methylsulfanylphenyl)pyrrolidine-2-carboxamide | 1-[(5-bromo-2-thienyl)sulfonyl]-N-[3-(methylthio)phenyl]prolinamide | 1-[(5-bromo-2-thienyl)sulfonyl]-N-[3-(methylthio)phenyl]pyrrolidine-2-carboxamide | 1-[(5-bromo-2-thiophenyl)sulfonyl]-N-[3-(methylthio)phenyl]-2-pyrrolidinecarboxamide | MLS000531786 | SMR000136764 | cid_2961359 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17BrN2O3S3 |
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| Mol. Mass. | 461.417 |
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| SMILES | CSc1cccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Br)s2)c1 |
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| Structure | 
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