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TargetOrexin/Hypocretin receptor type 1
LigandBDBM79927
Substrate/Competitorn/a
Meas. Tech.Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1)
IC50 546.29±n/a nM
Citation PubChem, PC Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Orexin/Hypocretin receptor type 1
Name:Orexin/Hypocretin receptor type 1
Synonyms:HCRTR1 | Hypocretin receptor type 1 | OX1R_HUMAN | Orexin receptor type 1 | Orexin receptor type 1 (OR 1) | Orexin receptor type 1 (OR-1) | Orexin receptor type 1 (OX1) | Orexin receptor type 1 (OX1R) | Orexin receptor type 1 (OxR1) | Ox1r
Type:Protein
Mol. Mass.:47554.50
Organism:Homo sapiens (Human)
Description:O43613
Residue:425
Sequence:
MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
TTVLP
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BDBM79927
n/a
NameBDBM79927
Synonyms:MLS000937074 | N-(3-methylsulfanylphenyl)-1-thiophen-2-ylsulfonyl-piperidine-3-carboxamide | N-(3-methylsulfanylphenyl)-1-thiophen-2-ylsulfonylpiperidine-3-carboxamide | N-[3-(methylthio)phenyl]-1-(2-thienylsulfonyl)nipecotamide | N-[3-(methylthio)phenyl]-1-thiophen-2-ylsulfonyl-3-piperidinecarboxamide | SMR000621864 | cid_22429402
TypeSmall organic molecule
Emp. Form.C17H20N2O3S3
Mol. Mass.396.547
SMILESCSc1cccc(NC(=O)C2CCCN(C2)S(=O)(=O)c2cccs2)c1
Structure
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