| Reaction Details |
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 | Report a problem with these data |
| Target | Orexin/Hypocretin receptor type 1 |
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| Ligand | BDBM76028 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) |
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| IC50 | 385.91±n/a nM |
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| Citation |  PubChem, PC Homogeneous Time Resolved Fluorescence (HTRF)-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Orexin/Hypocretin receptor type 1 |
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| Name: | Orexin/Hypocretin receptor type 1 |
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| Synonyms: | HCRTR1 | Hypocretin receptor type 1 | OX1R_HUMAN | Orexin receptor type 1 | Orexin receptor type 1 (OR 1) | Orexin receptor type 1 (OR-1) | Orexin receptor type 1 (OX1) | Orexin receptor type 1 (OX1R) | Orexin receptor type 1 (OxR1) | Ox1r |
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| Type: | Protein |
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| Mol. Mass.: | 47554.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O43613 |
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| Residue: | 425 |
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| Sequence: | MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
TTVLP
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| BDBM76028 |
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| n/a |
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| Name | BDBM76028 |
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| Synonyms: | 5-fluoranyl-3-methyl-N-(2-methyl-1,3-benzothiazol-6-yl)-1-benzofuran-2-carboxamide | 5-fluoro-3-methyl-N-(2-methyl-1,3-benzothiazol-6-yl)-1-benzofuran-2-carboxamide | 5-fluoro-3-methyl-N-(2-methyl-1,3-benzothiazol-6-yl)-2-benzofurancarboxamide | 5-fluoro-3-methyl-N-(2-methyl-1,3-benzothiazol-6-yl)coumarilamide | MLS002170106 | SMR001250428 | cid_9085542 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13FN2O2S |
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| Mol. Mass. | 340.371 |
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| SMILES | Cc1nc2ccc(NC(=O)c3oc4ccc(F)cc4c3C)cc2s1 |
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| Structure | 
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