| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Ligand | BDBM80197 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | >100000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 23013.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_21955158 |
|---|
| Residue: | 199 |
|---|
| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
|
|
|---|
| BDBM80197 |
|---|
| n/a |
|---|
| Name | BDBM80197 |
|---|
| Synonyms: | 4-[[(E)-3-(2-methoxyphenyl)prop-2-enylidene]amino]-3-(4-pyridyl)-1H-1,2,4-triazole-5-thione | 4-[[(E)-3-(2-methoxyphenyl)prop-2-enylidene]amino]-3-pyridin-4-yl-1H-1,2,4-triazole-5-thione | 4-{[3-(2-methoxyphenyl)-2-propen-1-ylidene]amino}-5-(4-pyridinyl)-4H-1,2,4-triazole-3-thiol | MLS000676781 | SMR000271794 | cid_1603830 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H15N5OS |
|---|
| Mol. Mass. | 337.399 |
|---|
| SMILES | COc1ccccc1C=CC=Nn1c(n[nH]c1=S)-c1ccncc1 |w:11.12,8.8| |
|---|
| Structure | 
|
|---|
Search and Browse
