| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
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| Ligand | BDBM80384 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen |
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| Temperature | 298.15±n/a K |
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| IC50 | 1810±77 nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3G |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
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| Synonyms: | ABC3G_HUMAN | APOBEC3G |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46419.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13399304 |
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| Residue: | 384 |
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| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
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| BDBM80384 |
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| n/a |
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| Name | BDBM80384 |
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| Synonyms: | 2-[N-(benzenesulfonyl)-2-methoxyanilino]-N-(1,3-benzodioxol-5-yl)acetamide | MLS000110102 | N-(1,3-benzodioxol-5-yl)-2-(N-besyl-2-methoxy-anilino)acetamide | N-(1,3-benzodioxol-5-yl)-2-[(2-methoxyphenyl)-(phenylsulfonyl)amino]ethanamide | SMR000106034 | cid_1138020 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20N2O6S |
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| Mol. Mass. | 440.469 |
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| SMILES | COc1ccccc1N(CC(=O)Nc1ccc2OCOc2c1)S(=O)(=O)c1ccccc1 |
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| Structure | 
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