| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
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| Ligand | BDBM40679 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen |
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| Temperature | 298.15±n/a K |
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| IC50 | 1320±101 nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3G |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
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| Synonyms: | ABC3G_HUMAN | APOBEC3G |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46419.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13399304 |
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| Residue: | 384 |
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| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
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| BDBM40679 |
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| n/a |
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| Name | BDBM40679 |
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| Synonyms: | 1-ethyl-2,6-dimethyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2-ium iodide | 1-ethyl-2,6-dimethyl-3,4-dihydropyrrolo[1,2-a]pyrazin-2-ium;iodide | MLS000532590 | SMR000137529 | cid_2826925 |
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| Type | Small organic molecule |
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| Emp. Form. | C11H17N2 |
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| Mol. Mass. | 177.2655 |
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| SMILES | CCC1=[N+](C)CCn2c(C)ccc12 |c:2| |
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| Structure | 
|
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