Ki Summary

Reaction Details

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Target

DNA dC->dU-editing enzyme APOBEC-3G

Ligand

BDBM61313

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen

Temperature

298.15±n/a K

IC50

3490±210 nM

Comments

extracted

Citation

PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

DNA dC->dU-editing enzyme APOBEC-3G

Name:

DNA dC->dU-editing enzyme APOBEC-3G

Synonyms:

ABC3G_HUMAN | APOBEC3G

Type:

Enzyme Catalytic Domain

Mol. Mass.:

46419.54

Organism:

Homo sapiens (Human)

Description:

gi_13399304

Residue:

384

Sequence:

MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN

BDBM61313

n/a

Name

BDBM61313

Synonyms:

10-hydroxy-11-(4-methyl-4-morpholin-4-iumyl)undecanoic acid methyl ester;iodide | 10-hydroxy-11-(4-methylmorpholin-4-ium-4-yl)undecanoic acid methyl ester;iodide | 4-(2-Hydroxy-10-methoxycarbonyl-decyl)-4-methyl-morpholin-4-ium | MLS001030075 | SMR000427263 | cid_16682274 | methyl 10-hydroxy-11-(4-methylmorpholin-4-ium-4-yl)undecanoate;iodide | methyl 11-(4-methylmorpholin-4-ium-4-yl)-10-oxidanyl-undecanoate;iodide

Type

Small organic molecule

Emp. Form.

C17H34NO4

Mol. Mass.

316.4556

SMILES

COC(=O)CCCCCCCCC(O)C[N+]1(C)CCOCC1

Structure