| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
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| Ligand | BDBM80537 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen |
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| Temperature | 298.15±n/a K |
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| IC50 | 1720±152 nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of APOBEC3A DNA Deaminase Inhibitors via a A3G counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3G |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
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| Synonyms: | ABC3G_HUMAN | APOBEC3G |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46419.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13399304 |
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| Residue: | 384 |
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| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
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| BDBM80537 |
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| n/a |
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| Name | BDBM80537 |
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| Synonyms: | 4-(2-Chloro-phenylcarbamoyl)-1-methyl-pyridinium | MLS001203658 | N-(2-chlorophenyl)-1-methyl-4-pyridin-1-iumcarboxamide;iodide | N-(2-chlorophenyl)-1-methyl-pyridin-1-ium-4-carboxamide;iodide | N-(2-chlorophenyl)-1-methylpyridin-1-ium-4-carboxamide;iodide | SMR000505130 | cid_23724360 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H12ClN2O |
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| Mol. Mass. | 247.7 |
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| SMILES | C[n+]1ccc(cc1)C(=O)Nc1ccccc1Cl |
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| Structure | 
|
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