| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM80361 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 1350±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
|
|
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| BDBM80361 |
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| n/a |
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| Name | BDBM80361 |
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| Synonyms: | 5-(diethylamino)-2-hydroximino-valeric acid ethyl ester;iodomethane | 5-(diethylamino)-2-hydroxyiminopentanoic acid ethyl ester;iodomethane | MLS000047831 | SMR000033832 | cid_6411257 | ethyl (2Z)-5-(diethylamino)-2-(hydroxyimino)pentanoate | ethyl 5-(diethylamino)-2-hydroxyimino-pentanoate;iodanylmethane | ethyl 5-(diethylamino)-2-hydroxyiminopentanoate;iodomethane |
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| Type | Small organic molecule |
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| Emp. Form. | C11H22N2O3 |
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| Mol. Mass. | 230.304 |
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| SMILES | CCOC(=O)C(CCCN(CC)CC)N=O |
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| Structure | 
|
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