| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM80415 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 1670±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
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|
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| BDBM80415 |
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| n/a |
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| Name | BDBM80415 |
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| Synonyms: | 1,3,3-Trimethyl-2-[2-(methyl-phenyl-amino)-vinyl]-3H-indolium | MLS000556742 | SMR000173748 | cid_11958735 | methyl-phenyl-[(2Z)-2-(1,3,3-trimethyl-2-indolylidene)ethylidene]ammonium;iodide | methyl-phenyl-[(2Z)-2-(1,3,3-trimethylindol-2-ylidene)ethylidene]azanium;iodide | methyl-phenyl-[(2Z)-2-(1,3,3-trimethylindolin-2-ylidene)ethylidene]ammonium;iodide |
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| Type | Small organic molecule |
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| Emp. Form. | C20H23N2 |
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| Mol. Mass. | 291.4095 |
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| SMILES | CN(\C=C\C1=[N+](C)c2ccccc2C1(C)C)c1ccccc1 |c:4| |
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| Structure | 
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