| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM80613 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 8260±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
|
|
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| BDBM80613 |
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| n/a |
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| Name | BDBM80613 |
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| Synonyms: | 1-(2,3,4-Trimethoxy-benzyl)-piperazine | 1-(2,3,4-trimethoxybenzyl)piperazine;hydrochloride | 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine;hydrochloride | MLS001240268 | SMR000674573 | TRIMETAZIDINE | cid_9926449 |
|---|
| Type | Small organic molecule |
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| Emp. Form. | C14H22N2O3 |
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| Mol. Mass. | 266.3361 |
|---|
| SMILES | COc1ccc(CN2CCNCC2)c(OC)c1OC |
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| Structure | 
|
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