Reaction Details |
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Target | C-C chemokine receptor type 6 |
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Ligand | BDBM79971 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay |
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IC50 | 15500±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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C-C chemokine receptor type 6 |
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Name: | C-C chemokine receptor type 6 |
Synonyms: | C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22 |
Type: | Enzyme |
Mol. Mass.: | 42510.84 |
Organism: | Homo sapiens (Human) |
Description: | P51684 |
Residue: | 374 |
Sequence: | MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
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BDBM79971 |
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n/a |
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Name | BDBM79971 |
Synonyms: | 2-(1-Butyryl-2,2-dimethyl-3-thioxo-2,3-dihydro-1H-quinolin-4-ylidene)-[1,3]dithiole-4,5-dicarboxylic acid dimethyl ester | 2-(1-butyryl-2,2-dimethyl-3-thioxo-4-quinolylidene)-1,3-dithiole-4,5-dicarboxylic acid dimethyl ester | 2-[2,2-dimethyl-1-(1-oxobutyl)-3-sulfanylidene-4-quinolinylidene]-1,3-dithiole-4,5-dicarboxylic acid dimethyl ester | MLS000120807 | SMR000118274 | cid_3125473 | dimethyl 2-(1-butanoyl-2,2-dimethyl-3-sulfanylidene-quinolin-4-ylidene)-1,3-dithiole-4,5-dicarboxylate | dimethyl 2-(1-butanoyl-2,2-dimethyl-3-sulfanylidenequinolin-4-ylidene)-1,3-dithiole-4,5-dicarboxylate |
Type | Small organic molecule |
Emp. Form. | C22H23NO5S3 |
Mol. Mass. | 477.617 |
SMILES | [#6]-[#6]-[#6]-[#6](=O)-[#7]1-c2ccccc2\[#6](=[#6]-2\[#16]-[#6](-[#6](=O)-[#8]-[#6])=[#6](-[#16]-2)-[#6](=O)-[#8]-[#6])-[#6](=S)C1([#6])[#6] |c:20| |
Structure |
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