Ki Summary

Reaction Details

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Target

C-C chemokine receptor type 6

Ligand

BDBM51789

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay

IC50

39600±n/a nM

Citation

PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

C-C chemokine receptor type 6

Name:

C-C chemokine receptor type 6

Synonyms:

Type:

Enzyme

Mol. Mass.:

42510.84

Organism:

Homo sapiens (Human)

Description:

P51684

Residue:

374

Sequence:

MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM

BDBM51789

n/a

Name

BDBM51789

Synonyms:

2-[(5Z)-5-[1-[2-(3-bromoanilino)-2-keto-ethyl]-2-keto-indolin-3-ylidene]-4-keto-2-thioxo-thiazolidin-3-yl]ethanesulfonic acid | 2-[(5Z)-5-[1-[2-(3-bromoanilino)-2-oxoethyl]-2-oxo-3-indolylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]ethanesulfonic acid | 2-[(5Z)-5-[1-[2-(3-bromoanilino)-2-oxoethyl]-2-oxoindol-3-ylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid | 2-[(5Z)-5-[1-[2-[(3-bromophenyl)amino]-2-oxidanylidene-ethyl]-2-oxidanylidene-indol-3-ylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]ethanesulfonic acid | MLS000923796 | SMR000620081 | cid_1637842

Type

Small organic molecule

Emp. Form.

C21H16BrN3O6S3

Mol. Mass.

582.467

SMILES

OS(=O)(=O)CCN1C(=S)S\C(C1=O)=C1/C(=O)N(CC(=O)Nc2cccc(Br)c2)c2ccccc12

Structure