| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase HKDC1 [W721R] |
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| Ligand | BDBM47546 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) |
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| IC50 | 7000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase HKDC1 [W721R] |
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| Name: | Hexokinase HKDC1 [W721R] |
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| Synonyms: | HKDC1 | HKDC1_HUMAN | putative hexokinase HKDC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 102520.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156151420 |
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| Residue: | 917 |
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| Sequence: | MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
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| BDBM47546 |
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| n/a |
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| Name | BDBM47546 |
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| Synonyms: | 2-[[(E)-1-oxo-3-thiophen-2-ylprop-2-enyl]amino]-4-phenyl-3-thiophenecarboxylic acid | 4-phenyl-2-[[(E)-3-(2-thienyl)acryloyl]amino]-3-thenoic acid | 4-phenyl-2-[[(E)-3-thiophen-2-ylprop-2-enoyl]amino]thiophene-3-carboxylic acid | MLS000773385 | SMR000364116 | cid_1177253 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H13NO3S2 |
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| Mol. Mass. | 355.431 |
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| SMILES | OC(=O)c1c(NC(=O)\C=C\c2cccs2)scc1-c1ccccc1 |
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| Structure | 
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