| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM31715 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| IC50 | 14960±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for inhibitors of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM31715 |
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| n/a |
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| Name | BDBM31715 |
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| Synonyms: | 3-[(4Z)-4-[(E)-3-(2-furanyl)prop-2-enylidene]-3-methyl-5-oxo-1-pyrazolyl]benzoic acid | 3-[(4Z)-4-[(E)-3-(2-furyl)prop-2-enylidene]-5-keto-3-methyl-2-pyrazolin-1-yl]benzoic acid | 3-[(4Z)-4-[(E)-3-(furan-2-yl)prop-2-enylidene]-3-methyl-5-oxidanylidene-pyrazol-1-yl]benzoic acid | 3-[(4Z)-4-[(E)-3-(furan-2-yl)prop-2-enylidene]-3-methyl-5-oxopyrazol-1-yl]benzoic acid | 3-{4-[3-(2-furyl)-2-propenylidene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazol-1-yl}benzoic acid | MLS000549909 | SMR000113614 | cid_9549698 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14N2O4 |
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| Mol. Mass. | 322.3148 |
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| SMILES | OC(=O)c1cccc(c1)-n1[nH]c(=C)c(=CC=Cc2ccco2)c1=O |w:14.15| |
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| Structure | 
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