| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cysteine protease ATG4B |
|---|
| Ligand | BDBM80846 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. |
|---|
| IC50 | 2360±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Cysteine protease ATG4B |
|---|
| Name: | Cysteine protease ATG4B |
|---|
| Synonyms: | APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44279.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_47132611 |
|---|
| Residue: | 393 |
|---|
| Sequence: | MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
|
|
|
|---|
| BDBM80846 |
|---|
| n/a |
|---|
| Name | BDBM80846 |
|---|
| Synonyms: | 2-[[3-(cyclohexylmethyl)-4-keto-quinazolin-2-yl]thio]propionic acid ethyl ester | 2-[[3-(cyclohexylmethyl)-4-oxo-2-quinazolinyl]thio]propanoic acid ethyl ester | MLS000537883 | SMR000144125 | cid_2959700 | ethyl 2-[3-(cyclohexylmethyl)-4-oxidanylidene-quinazolin-2-yl]sulfanylpropanoate | ethyl 2-[3-(cyclohexylmethyl)-4-oxoquinazolin-2-yl]sulfanylpropanoate | ethyl 2-{[3-(cyclohexylmethyl)-4-oxo-3,4-dihydro-2-quinazolinyl]thio}propanoate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H26N2O3S |
|---|
| Mol. Mass. | 374.497 |
|---|
| SMILES | CCOC(=O)C(C)Sc1nc2ccccc2c(=O)n1CC1CCCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
