| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteine protease ATG4B |
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| Ligand | BDBM80880 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. |
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| IC50 | 399±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cysteine protease ATG4B |
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| Name: | Cysteine protease ATG4B |
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| Synonyms: | APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44279.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_47132611 |
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| Residue: | 393 |
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| Sequence: | MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
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| BDBM80880 |
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| n/a |
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| Name | BDBM80880 |
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| Synonyms: | 7-Ethyl-5-(4-nitro-phenyl)-2-phenyl-3H-benzo[e][1,2,4]triazepine | 7-ethyl-5-(4-nitrophenyl)-2-phenyl-4H-1,3,4-benzotriazepine | MLS000566936 | SMR000177233 | cid_3135949 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18N4O2 |
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| Mol. Mass. | 370.4039 |
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| SMILES | CCc1ccc2N=C(N=[NH+][C-](c3ccc(cc3)[N+]([O-])=O)c2c1)c1ccccc1 |c:6,8| |
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| Structure | 
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