| Reaction Details |
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 | Report a problem with these data |
| Target | Cysteine protease ATG4B |
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| Ligand | BDBM42035 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. |
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| IC50 | 5280±n/a nM |
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| Citation |  PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cysteine protease ATG4B |
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| Name: | Cysteine protease ATG4B |
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| Synonyms: | APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 44279.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_47132611 |
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| Residue: | 393 |
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| Sequence: | MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
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| BDBM42035 |
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| n/a |
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| Name | BDBM42035 |
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| Synonyms: | 4-[(3aR,4S,9bS)-8-[(4-methoxyphenyl)sulfamoyl]-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinolin-4-yl]benzoic acid | UNM000011068501 | cid_5322407 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H24N2O5S |
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| Mol. Mass. | 476.544 |
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| SMILES | COc1ccc(NS(=O)(=O)c2ccc3N[C@@H]([C@@H]4CC=C[C@@H]4c3c2)c2ccc(cc2)C(O)=O)cc1 |c:18| |
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| Structure | 
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