| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hexokinase-1 |
|---|
| Ligand | BDBM80798 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay |
|---|
| EC50 | 17400±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Hexokinase-1 |
|---|
| Name: | Hexokinase-1 |
|---|
| Synonyms: | Brain form hexokinase | HK I | HK1 | HXK1_HUMAN | Hexokinase type I | Hexokinase-1 | hexokinase-1 isoform HKI |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 102488.34 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_11382 |
|---|
| Residue: | 917 |
|---|
| Sequence: | MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV
EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDD
IRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA
VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLRTEASS
|
|
|
|---|
| BDBM80798 |
|---|
| n/a |
|---|
| Name | BDBM80798 |
|---|
| Synonyms: | 3-[[5-(2,4-dimethoxyphenyl)-6H-1,3,4-thiadiazin-2-yl]amino]-N,N,4-trimethyl-benzenesulfonamide | 3-[[5-(2,4-dimethoxyphenyl)-6H-1,3,4-thiadiazin-2-yl]amino]-N,N,4-trimethylbenzenesulfonamide | MLS000761165 | SMR000365297 | cid_4882584 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H24N4O4S2 |
|---|
| Mol. Mass. | 448.559 |
|---|
| SMILES | COc1ccc(C2=NN=C(Nc3cc(ccc3C)S(=O)(=O)N(C)C)SC2)c(OC)c1 |t:6,8| |
|---|
| Structure | 
|
|---|
Search and Browse
