| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase-1 |
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| Ligand | BDBM34233 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay |
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| EC50 | 41900±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase-1 |
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| Name: | Hexokinase-1 |
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| Synonyms: | Brain form hexokinase | HK I | HK1 | HXK1_HUMAN | Hexokinase type I | Hexokinase-1 | hexokinase-1 isoform HKI |
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| Type: | PROTEIN |
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| Mol. Mass.: | 102488.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_11382 |
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| Residue: | 917 |
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| Sequence: | MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV
EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDD
IRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA
VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLRTEASS
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| BDBM34233 |
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| n/a |
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| Name | BDBM34233 |
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| Synonyms: | 2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen) | 2-phenyl-1,2-benzisoselazol-3(2H)-one | 2-phenyl-1,2-benzoselenazol-3-one | 2-phenylbenzo[d][1,2]selenazol-3(2H)-one | CHEMBL51085 | EBSELEN | Ebselen (C5) | MLS000028488 | SMR000058445 | cid_3194 | med.21724, Compound 153 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9NOSe |
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| Mol. Mass. | 274.18 |
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| SMILES | O=c1n([se]c2ccccc12)-c1ccccc1 |
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| Structure | 
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