| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase |
|---|
| Ligand | BDBM81097 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay |
|---|
| IC50 | 3660±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of Plasmodium falciparum Glucose-6-phosphate dehydrogenase via a fluorescence intensity assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase |
|---|
| Name: | Glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase |
|---|
| Synonyms: | n/a |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 109731.64 |
|---|
| Organism: | Plasmodium falciparum 3D7 |
|---|
| Description: | gi_12381848 |
|---|
| Residue: | 950 |
|---|
| Sequence: | MEYETSLKCLDEIRCVNNVKYMETEDLTDFNKKSAYYICKEIYEKQLSNENGYVVIGLSG
GKTPIDVYKNMCAIKDIKIDKNKLIFFIIDERYKNDDHKFSNYNNIKFLFDELNINKETQ
LYKPDTKKDLVSCIRDYNEQIKSMIEKYKKIDIVILGMGSDFHIASLFPNVYYNIYMNNY
QNNYIYEDNETIRSLNADNNVNLSLLNEQVYFTTTNNFDVRKRITVSLNLLSNSTSKIFL
LNTADKLNLWKNMLLNFYVNPNYNLYPAFKMIDSSNTTVIACGHKNYSKMLEDLYVQKDE
ALSPISNNNVENKNELLTIVIFGCSGDLAKKKIYPALFKLFCNNLLPKNIIIIGFARTGQ
DFESFFNKIAIYLKISLNSYKNLSVFEKAERLNSFKSKCRYFIGNYLSPESFENFDVYIT
QEERIALGCCGQKGNEKHKQVNVTSQFPNNHTSINIINNIDNGCESPMLTDSPKRYPCSS
SYSSTSGTAVCPYSSQHDVKPSNNGCPYLSSQANTSDSSGCPYISYHTNKSGHLGCPYTI
TRMLYLALPPHVFVSTLQNYKKYCLNKNRINKILLEKPFGKDLESFKILSKQILETFPEK
NIYRIDHYLGKDMVSGLLKLKFTNIFLLSLMNRHFIKCIKITLKETKGVYGRGQYFDPYG
IIRDVMQNHMLQLLALITMEHPTDLNDKSIQNEKIKILKSIASIKLEDTVIGQYVKSNND
DTNNNINSNISENASIDKSKINHSYHDDPHVDPNSITPTFCACVLYINSINWHGVPIILK
AGKGLNNDICEIKIQFHNIMGSSDESMYNNEFVIILQPVEGIYLKLMIKKMGSEEMEEVQ
LNLSLNENNNKAYVPEAYETLLSECYKGYKRKFISDEELYESWRIFTPLLNELQEKHIKP
LSYPFGSSGPQEAYDLVRKYYNYGKNYATTAKFCRKSSYYDDSLFDNMRE
|
|
|
|---|
| BDBM81097 |
|---|
| n/a |
|---|
| Name | BDBM81097 |
|---|
| Synonyms: | (E)-N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-(5-methyl-2-furanyl)-2-propenamide | (E)-N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-(5-methyl-2-furyl)acrylamide | (E)-N-(2,3-dihydro-1,4-benzodioxin-3-ylmethyl)-3-(5-methylfuran-2-yl)prop-2-enamide | MLS001017459 | SMR000353699 | cid_6223754 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H17NO4 |
|---|
| Mol. Mass. | 299.3212 |
|---|
| SMILES | Cc1ccc(\C=C\C(=O)NCC2COc3ccccc3O2)o1 |
|---|
| Structure | 
|
|---|
Search and Browse
