| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-6-phosphate 1-dehydrogenase |
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| Ligand | BDBM34435 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase |
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| IC50 | >80000±n/a nM |
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| Citation |  PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Glucose-6-phosphate 1-dehydrogenase |
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| Name: | Glucose-6-phosphate 1-dehydrogenase |
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| Synonyms: | G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b |
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| Type: | Enzyme |
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| Mol. Mass.: | 59258.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11413 |
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| Residue: | 515 |
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| Sequence: | MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
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| BDBM34435 |
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| n/a |
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| Name | BDBM34435 |
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| Synonyms: | 4-cyano-3-methyl-5-[[1-oxo-2-[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]thio]ethyl]amino]-2-thiophenecarboxylic acid ethyl ester | 5-[[2-[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]acetyl]amino]-4-cyano-3-methyl-thiophene-2-carboxylic acid ethyl ester | MLS000051364 | SMR000079493 | cid_2222655 | ethyl 4-cyano-3-methyl-5-[2-[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanoylamino]thiophene-2-carboxylate | ethyl 5-({[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]acetyl}amino)-4-cyano-3-methyl-2-thiophenecarboxylate | ethyl 5-[[2-[(5-benzyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetyl]amino]-4-cyano-3-methylthiophene-2-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C20H18N4O4S2 |
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| Mol. Mass. | 442.511 |
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| SMILES | CCOC(=O)c1sc(NC(=O)CSc2nnc(Cc3ccccc3)o2)c(C#N)c1C |
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| Structure | 
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