| Reaction Details |
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 | Report a problem with these data |
| Target | Glucose-6-phosphate 1-dehydrogenase |
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| Ligand | BDBM47722 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase |
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| IC50 | >80000±n/a nM |
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| Citation |  PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Glucose-6-phosphate 1-dehydrogenase |
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| Name: | Glucose-6-phosphate 1-dehydrogenase |
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| Synonyms: | G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b |
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| Type: | Enzyme |
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| Mol. Mass.: | 59258.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11413 |
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| Residue: | 515 |
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| Sequence: | MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL
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|
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| BDBM47722 |
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| n/a |
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| Name | BDBM47722 |
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| Synonyms: | 5-cyano-4-ethyl-2-methyl-N-phenyl-6-sulfanylidene-1H-pyridine-3-carboxamide | 5-cyano-4-ethyl-2-methyl-N-phenyl-6-thioxo-1,6-dihydro-3-pyridinecarboxamide | 5-cyano-4-ethyl-2-methyl-N-phenyl-6-thioxo-1H-pyridine-3-carboxamide | MLS000532290 | SMR000137229 | cid_789551 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H15N3OS |
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| Mol. Mass. | 297.375 |
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| SMILES | CCc1c(C#N)c(=S)[nH]c(C)c1C(=O)Nc1ccccc1 |
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| Structure | 
|
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