Ki Summary

Reaction Details

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Target

Glucose-6-phosphate 1-dehydrogenase

Ligand

BDBM81110

Substrate/Competitor

n/a

Meas. Tech.

Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase

IC50

>80000±n/a nM

Citation

PubChem, PC Human Glucose-6-Phosphate Dehydrogenase Dose Response Selectivity Assay for Inhibitors of Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Glucose-6-phosphate 1-dehydrogenase

Name:

Glucose-6-phosphate 1-dehydrogenase

Synonyms:

G6PD | G6PD_HUMAN | Glucose 6-phosphate dehydrogenase (G6PD) | Glucose-6-phosphate 1-dehydrogenase | glucose-6-phosphate 1-dehydrogenase isoform b

Type:

Enzyme

Mol. Mass.:

59258.58

Organism:

Homo sapiens (Human)

Description:

P11413

Residue:

515

Sequence:

MAEQVALSRTQVCGILREELFQGDAFHQSDTHIFIIMGASGDLAKKKIYPTIWWLFRDGL
LPENTFIVGYARSRLTVADIRKQSEPFFKATPEEKLKLEDFFARNSYVAGQYDDAASYQR
LNSHMNALHLGSQANRLFYLALPPTVYEAVTKNIHESCMSQIGWNRIIVEKPFGRDLQSS
DRLSNHISSLFREDQIYRIDHYLGKEMVQNLMVLRFANRIFGPIWNRDNIACVILTFKEP
FGTEGRGGYFDEFGIIRDVMQNHLLQMLCLVAMEKPASTNSDDVRDEKVKVLKCISEVQA
NNVVLGQYVGNPDGEGEATKGYLDDPTVPRGSTTATFAAVVLYVENERWDGVPFILRCGK
ALNERKAEVRLQFHDVAGDIFHQQCKRNELVIRVQPNEAVYTKMMTKKPGMFFNPEESEL
DLTYGNRYKNVKLPDAYERLILDVFCGSQMHFVRSDELREAWRIFTPLLHQIELEKPKPI
PYIYGSRGPTEADELMKRVGFQYEGTYKWVNPHKL

BDBM81110

n/a

Name

BDBM81110

Synonyms:

2-[[(6-methoxy-8-quinolinyl)amino]methyl]phenol | 2-[[(6-methoxy-8-quinolyl)amino]methyl]phenol | 2-[[(6-methoxyquinolin-8-yl)amino]methyl]phenol | MLS000738207 | SMR000528574 | cid_279609

Type

Small organic molecule

Emp. Form.

C17H16N2O2

Mol. Mass.

280.3211

SMILES

COc1cc(NCc2ccccc2O)c2ncccc2c1

Structure