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TargetcAMP-dependent protein kinase type II-beta regulatory subunit
LigandBDBM81288
Substrate/Competitorn/a
Meas. Tech.Counterscreen for activators of the Protein Kinase A-R1A (PKA-R1A) complex
EC50 2155±n/a nM
Citation PubChem, PC Counterscreen for activators of the Protein Kinase A-R1A (PKA-R1A) complex: fluorescence polarization-based biochemical high throughput dose response assay to identify activators of the Protein Kinase A-R2B (PKA-R2B) complex PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
cAMP-dependent protein kinase type II-beta regulatory subunit
Name:cAMP-dependent protein kinase type II-beta regulatory subunit
Synonyms:KAP3_HUMAN | PRKAR2B
Type:PROTEIN
Mol. Mass.:46282.41
Organism:Homo sapiens (Human)
Description:EBI_11972
Residue:418
Sequence:
MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGTARFGHEGRTWGD
LGAAAGGGTPSKGVNFAEEPMQSDSEDGEEEEAAPADAGAFNAPVINRFTRRASVCAEAY
NPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEH
VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATS
PGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFSERLKVVDVIGTKVYNDG
EQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKP
RAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
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  Blast E-value cutoff:
BDBM81288
n/a
NameBDBM81288
Synonyms:8-Bromoguanosine 3',5'-cyclic monophosphate sodium salt | MLS000860011 | SMR000326870 | cid_23702959 | sodium;9-[(4aR,6R,7R,7aS)-2-oxidanidyl-7-oxidanyl-2-oxidanylidene-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-azanyl-8-bromanyl-3H-purin-6-one | sodium;9-[(4aR,6R,7R,7aS)-7-hydroxy-2-keto-2-oxido-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-6-yl]-2-amino-8-bromo-3H-purin-6-one | sodium;9-[(4aR,6R,7R,7aS)-7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-2-amino-8-bromo-3H-purin-6-one | sodium;9-[(4aR,6R,7R,7aS)-7-hydroxy-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphorin-6-yl]-2-amino-8-bromo-3H-purin-6-one
TypeSmall organic molecule
Emp. Form.C10H10BrN5O7P
Mol. Mass.423.094
SMILESNc1nc2n([C@@H]3O[C@@H]4COP([O-])(=O)O[C@H]4[C@H]3O)c(Br)nc2c(=O)[nH]1
Structure
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