| Reaction Details |
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 | Report a problem with these data |
| Target | Cell division protein FtsZ |
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| Ligand | BDBM81334 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescent Coupled Assay |
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| pH | 7.5±0 |
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| IC50 | 5.20e+4± 5.7e+3 nM |
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| Citation |  Läppchen, T; Pinas, VA; Hartog, AF; Koomen, GJ; Schaffner-Barbero, C; Andreu, JM; Trambaiolo, D; Löwe, J; Juhem, A; Popov, AV; den Blaauwen, T Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites. Chem Biol15:189-99 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Cell division protein FtsZ |
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| Name: | Cell division protein FtsZ |
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| Synonyms: | FTSZ_AQUAE | ftsZ |
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| Type: | Protein |
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| Mol. Mass.: | 40146.54 |
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| Organism: | Aquifex aeolicus |
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| Description: | O66809 |
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| Residue: | 367 |
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| Sequence: | MEEFVNPCKIKVIGVGGGGSNAVNRMYEDGIEGVELYAINTDVQHLSTLKVPNKIQIGEK
VTRGLGAGAKPEVGEEAALEDIDKIKEILRDTDMVFISAGLGGGTGTGAAPVIAKTAKEM
GILTVAVATLPFRFEGPRKMEKALKGLEKLKESSDAYIVIHNDKIKELSNRTLTIKDAFK
EVDSVLSKAVRGITSIVVTPAVINVDFADVRTTLEEGGLSIIGMGEGRGDEKADIAVEKA
VTSPLLEGNTIEGARRLLVTIWTSEDIPYDIVDEVMERIHSKVHPEAEIIFGAVLEPQEQ
DFIRVAIVATDFPEEKFQVGEKEVKFKVIKKEEKEEPKEEPKPLSDTTYLEEEEIPAVIR
RKNKRLL
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| BDBM81334 |
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| n/a |
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| Name | BDBM81334 |
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| Synonyms: | MeGTP (1b) |
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| Type | Small organic molecule |
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| Emp. Form. | C11H15N5O14P3 |
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| Mol. Mass. | 534.1848 |
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| SMILES | Cc1nc2c(nc(N)[nH]c2=O)n1[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OP(O)([O-])=O)C(O)C1O |r| |
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| Structure | 
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