| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H1 receptor |
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| Ligand | BDBM50062261 |
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| Substrate/Competitor | n/a |
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| Ki | 1.3±n/a nM |
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| Comments | PDSP_1912 |
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| Citation |  Tran, VT; Chang, RS; Snyder, SH Histamine H1 receptors identified in mammalian brain membranes with [3H]mepyramine. Proc Natl Acad Sci U S A75:6290-4 (1978) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine H1 receptor |
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| Name: | Histamine H1 receptor |
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| Synonyms: | HISTAMINE H1 | HRH1_RAT | Hrh1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55716.35 |
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| Organism: | RAT |
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| Description: | HISTAMINE H1 HRH1 RAT::P31390 |
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| Residue: | 486 |
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| Sequence: | MSFANTSSTFEDKMCEGNRTAMASPQLLPLVVVLSSISLVTVGLNLLVLYAVHSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLIMTKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLRYRTKTRASATILGAWFFSFLWVIPILGWHHFMPPAPELREDKC
ETDFYNVTWFKIMTAIINFYLPTLLMLWFYVKIYKAVRRHCQHRQLTNGSLPSFSELKLR
SDDTKEGAKKPGRESPWGVLKRPSRDPSVGLDQKSTSEDPKMTSPTVFSQEGERETRPCF
RLDIMQKQSVAEGDVRGSKANDQALSQPKMDEQSLNTCRRISETSEDQTLVDQQSFSRTT
DSDTSIEPGPGRVKSRSGSNSGLDYIKITWKRLRSHSRQYVSGLHLNRERKAAKQLGFIM
AAFILCWIPYFIFFMVIAFCKSCCSEPMHMFTIWLGYINSTLNPLIYPLCNENFKKTFKK
ILHIRS
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| BDBM50062261 |
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| n/a |
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| Name | BDBM50062261 |
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| Synonyms: | CHEMBL829 | Dimethyl-(2-methyl-3-phenothiazin-10-yl-propyl)-amine | Methylpromazine | N,N,2-trimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine | TRIMEPRAZINE | Temaril |
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| Type | Small organic molecule |
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| Emp. Form. | C18H22N2S |
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| Mol. Mass. | 298.446 |
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| SMILES | CC(CN(C)C)CN1c2ccccc2Sc2ccccc12 |
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| Structure | 
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