| Reaction Details |
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 | Report a problem with these data |
| Target | Bis(5'-adenosyl)-triphosphatase |
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| Ligand | BDBM81591 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibition Assay |
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| Ki | 2700±0.0 nM |
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| Citation |  Varnum, JM; Baraniak, J; Kaczmarek, R; Stec, WJ; Brenner, C Di-, tri- and tetra-5'-O-phosphorothioadenosyl substituted polyols as inhibitors of Fhit: Importance of the alpha-beta bridging oxygen and beta phosphorus replacement. BMC Chem Biol1:3 (2001) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Bis(5'-adenosyl)-triphosphatase |
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| Name: | Bis(5'-adenosyl)-triphosphatase |
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| Synonyms: | AP3A hydrolase | AP3Aase | Bis(5'adenosyl)-triphosphatase | Dinucleosidetriphosphatase | FHIT | FHIT_HUMAN | Fragile histidine triad protein |
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| Type: | Protein |
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| Mol. Mass.: | 16861.00 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P49789 |
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| Residue: | 147 |
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| Sequence: | MSFRFGQHLIKPSVVFLKTELSFALVNRKPVVPGHVLVCPLRPVERFHDLRPDEVADLFQ
TTQRVGTVVEKHFHGTSLTFSMQDGPEAGQTVKHVHVHVLPRKAGDFHRNDSIYEELQKH
DKEDFPASWRSEEEMAAEAAALRVYFQ
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| BDBM81591 |
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| n/a |
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| Name | BDBM81591 |
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| Synonyms: | AppppA analog, 16 (X=S) |
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| Type | Small organic molecule |
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| Emp. Form. | C33H43N17O16P3S3 |
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| Mol. Mass. | 1122.917 |
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| SMILES | Nc1ncnc2n(cnc12)[C@@H]1OC(COP([O-])(=S)NCC(CNP([S-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)OP([S-])(=O)OC[C@H]2OC([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O |r| |
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| Structure | 
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