| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Ligand | BDBM81711 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 1.2e+4±n/a nM |
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| Citation |  Kadam, RU; Garg, D; Roy, N Selective mapping of chemical space for Pseudomonas aeruginosa deacetylase LpxC inhibitory potential. Chem Biol Drug Des71:45-56 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Name: | UDP-3-O-acyl-N-acetylglucosamine deacetylase |
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| Synonyms: | LPXC_PSEAE | Protein envA | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC | UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase (LpxC) | UDP-3-O-acyl-GlcNAc deacetylase | UDP-3-O-acyl-GlcNAc deacetylase (LpxC) | envA | lpxC |
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| Type: | Enzyme |
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| Mol. Mass.: | 33428.15 |
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| Organism: | Pseudomonas aeruginosa |
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| Description: | P47205 |
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| Residue: | 303 |
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| Sequence: | MIKQRTLKNIIRATGVGLHSGEKVYLTLKPAPVDTGIVFCRTDLDPVVEIPARAENVGET
TMSTTLVKGDVKVDTVEHLLSAMAGLGIDNAYVELSASEVPIMDGSAGPFVFLIQSAGLQ
EQEAAKKFIRIKREVSVEEGDKRAVFVPFDGFKVSFEIDFDHPVFRGRTQQASVDFSSTS
FVKEVSRARTFGFMRDIEYLRSQNLALGGSVENAIVVDENRVLNEDGLRYEDEFVKHKIL
DAIGDLYLLGNSLIGEFRGFKSGHALNNQLLRTLIADKDAWEVVTFEDARTAPISYMRPA
AAV
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| BDBM81711 |
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| n/a |
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| Name | BDBM81711 |
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| Synonyms: | LpxC Inhibitor, L12 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H18N4O3 |
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| Mol. Mass. | 302.3284 |
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| SMILES | CCCCn1nc2ccccc2c1C1=N[C@H](CO1)C(=O)NO |r,t:15| |
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| Structure | 
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