| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M1 |
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| Ligand | BDBM81770 |
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| Substrate/Competitor | n/a |
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| Ki | 260±n/a nM |
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| Comments | PDSP_1797 |
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| Citation |  Bolden, C; Cusack, B; Richelson, E Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells. J Pharmacol Exp Ther260:576-80 (1992) [PubMed] |
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| More Info.: | Get all data from this article |
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| Muscarinic acetylcholine receptor M1 |
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| Name: | Muscarinic acetylcholine receptor M1 |
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| Synonyms: | ACM1_HUMAN | CHRM1 | Cholinergic receptor, muscarinic 1 | Cholinergic, muscarinic M1 |
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| Type: | Protein |
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| Mol. Mass.: | 51442.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11229 |
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| Residue: | 460 |
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| Sequence: | MNTSAPPAVSPNITVLAPGKGPWQVAFIGITTGLLSLATVTGNLLVLISFKVNTELKTVN
NYFLLSLACADLIIGTFSMNLYTTYLLMGHWALGTLACDLWLALDYVASNASVMNLLLIS
FDRYFSVTRPLSYRAKRTPRRAALMIGLAWLVSFVLWAPAILFWQYLVGERTVLAGQCYI
QFLSQPIITFGTAMAAFYLPVTVMCTLYWRIYRETENRARELAALQGSETPGKGGGSSSS
SERSQPGAEGSPETPPGRCCRCCRAPRLLQAYSWKEEEEEDEGSMESLTSSEGEEPGSEV
VIKMPMVDPEAQAPTKQPPRSSPNTVKRPTKKGRDRAGKGQKPRGKEQLAKRKTFSLVKE
KKAARTLSAILLAFILTWTPYNIMVLVSTFCKDCVPETLWELGYWLCYVNSTINPMCYAL
CNKAFRDTFRLLLLCRWDKRRWRKIPKRPGSVHRTPSRQC
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| BDBM81770 |
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| n/a |
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| Name | BDBM81770 |
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| Synonyms: | CAS_82650-83-7 | NSC_3086153 | TENILAPINE |
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| Type | Small organic molecule |
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| Emp. Form. | C17H16N4S2 |
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| Mol. Mass. | 340.466 |
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| SMILES | CN1CCN(CC1)C1=Nc2cscc2C(=CC#N)c2cscc12 |w:15.17,t:8| |
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| Structure | 
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